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FAT3 Rabbit pAb (bs-11081R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-11081R
英文名稱 FAT3 Rabbit pAb
中文名稱 鈣粘蛋白15抗體
別    名 Cadherin family member 15; CDHF15; CDHR10; FAT tumor suppressor homolog 3; Fat3; FAT3_HUMAN; hFat3; Protocadherin Fat 3.  
研究領域 神經生物學  細胞粘附分子  細胞骨架  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 512 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDHF15/FAT3: 601-800/4589 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.

Function:
May play a role in the interactions between neurites derived from specific subsets of neurons during development.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).

Tissue Specificity:
Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate.

Similarity:
Contains 33 cadherin domains.
Contains 4 EGF-like domains.
Contains 1 laminin G-like domain.

SWISS:
Q8TDW7

Gene ID:
120114

Database links:

Entrez Gene: 120114 Human

Omim: 612483 Human

SwissProt: Q8TDW7 Human

Unigene: 98523 Human



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