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GALNT7 Rabbit pAb (bs-16223R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-16223R
英文名稱 GALNT7 Rabbit pAb
中文名稱 GalNAc-T7蛋白抗體
別    名 GalNAc T7; GalNAc-T7; GalNAcT7; GALNT 7; Galnt7; GALT7_HUMAN; N acetylgalactosaminyltransferase 7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; Polypeptide N acetylgalactosaminyltransferase 7; pp GaNTase 7; pp-GaNTase 7; Protein UDP acetylgalactosaminyltransferase 7; Protein-UDP acetylgalactosaminyltransferase 7; UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 7; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7.  
研究領域 細胞生物  免疫學  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GALNT7: 321-420/657 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation. [provided by RefSeq, Jul 2008]

Function:
Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified.

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.

Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.

SWISS:
Q86SF2

Gene ID:
51809

Database links:

Entrez Gene: 51809 Human

Entrez Gene: 108150 Mouse

Entrez Gene: 100171466 Orangutan

Entrez Gene: 29750 Rat

Omim: 605005 Human

SwissProt: Q86SF2 Human

SwissProt: Q80VA0 Mouse

SwissProt: Q5RFJ6 Orangutan

SwissProt: Q9R0C5 Rat

Unigene: 548088 Human

Unigene: 62886 Mouse

Unigene: 207200 Rat



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