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BACH1 Rabbit pAb (bs-8768R)  
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產品編號 bs-8768R
英文名稱 BACH1 Rabbit pAb
中文名稱 轉錄調節蛋白BACH1.3抗體
別    名 BACH 1; BACH 1.3; Bach1; BACH1_HUMAN; Basic leucine zipper transcription factor 1; basic region leucine zipper transcriptional regulator BACH1; BTB and CNC homolog 1; BTB and CNC homology 1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; HA2303; OTTHUMP00000096563; OTTHUMP00000096564; Transcription regulator protein BACH1.  
研究領域 細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 82 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BACH1: 501-600/736 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]

Function:
Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. CNC subfamily.
Contains 1 BTB (POZ) domain.
Contains 1 bZIP domain.

SWISS:
O14867

Gene ID:
571

Database links:

Entrez Gene: 571 Human

Entrez Gene: 12013 Mouse

Entrez Gene: 304127 Rat

Omim: 602751 Human

SwissProt: O14867 Human

SwissProt: P97302 Mouse

Unigene: 154276 Human

Unigene: 721915 Human

Unigene: 26147 Mouse

Unigene: 29793 Rat



產品圖片
Sample: Lane 1: Human HeLa cell lysates Lane 2: Human 293T cell lysates Lane 3: Human MCF-7 cell lysates Primary: Anti-BACH1 (bs-8768R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 82 kDa Observed band size: 105 kDa
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