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NFS1 Rabbit pAb (bs-19227R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-19227R
英文名稱 NFS1 Rabbit pAb
中文名稱 半胱氨酸脫硫酶NFS1抗體
別    名 Cysteine desulfurase; Cysteine desulfurase, mitochondrial; HUSSY 08; IscS; mitochondrial; NFS1; NFS1 nitrogen fixation 1; NFS1 nitrogen fixation 1 homolog(S. cerevisiae); NFS1_HUMAN; NIFS; nitrogen fixation 1(S. cerevisiae, homolog); nitrogen fixation gene 1; nitrogen-fixing bacteria S, homolog of; nitrogen-fixing bacteria S-like protein; OTTHUMP00000030799.  
研究領域 腫瘤  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse,Saccharomyces cerevisiae)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NFS1: 261-360/457 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]

Function:
Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron-sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.

Subcellular Location:
Cytoplasm. Nucleus and Mitochondrion.

Tissue Specificity:
Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas.

Similarity:
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

SWISS:
Q9Y697

Gene ID:
9054

Database links:

Entrez Gene: 9054 Human

Entrez Gene: 18041 Mouse

Entrez Gene: 84594 Rat

Omim: 603485 Human

SwissProt: Q9Y697 Human

SwissProt: Q9Z1J3 Mouse

SwissProt: Q99P39 Rat

Unigene: 194692 Human

Unigene: 283604 Mouse

Unigene: 3151 Rat



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