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NUP53 Rabbit pAb (bs-19546R)  
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產品編號 bs-19546R
英文名稱 NUP53 Rabbit pAb
中文名稱 核孔復合蛋白Nup53抗體
別    名 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP 44; MP-44; NP 44; NP44; Nuclear pore complex protein 53kDa; Nuclear pore complex protein Nup 53; Nuclear pore complex protein Nup53; Nuclear pore protein NUP 53; Nuclear pore protein NUP53; Nucleoporin 35kDa; Nucleoporin 53kDa; Nucleoporin Nup 35; Nucleoporin NUP 53; Nucleoporin Nup35; Nucleoporin NUP53; NUP 35; Nup 53; NUP35; NUP53; NUP53_HUMAN.  
研究領域 細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUP53: 241-326/326 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013]

Function:
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.

Subcellular Location:
Nucleus > nuclear pore complex. Nucleus membrane. Tightly associated with the nuclear membrane and lamina.

Similarity:
Belongs to the Nup53 family.
Contains 1 RRM Nup35-type domain.

SWISS:
Q8NFH5

Gene ID:
129401

Database links:

Entrez Gene: 129401 Human

Entrez Gene: 511248 Cow

Entrez Gene: 478830 Dog

Entrez Gene: 100054143 Horse

Entrez Gene: 69482 Mouse

Entrez Gene: 295692 Rat

Entrez Gene: 337461 Zebrafish

Omim: 608140 Human

SwissProt: Q8NFH5 Human

SwissProt: Q8R4R6 Mouse

SwissProt: Q68FY1 Rat

SwissProt: Q6P6X9 Zebrafish

Unigene: 180591 Human

Unigene: 29200 Mouse

Unigene: 203627 Rat

Unigene: 5851 Zebrafish



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