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Rabbit Anti-UBE2E3/APC Conjugated antibody (bs-8352R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8352R-APC
英文名稱 Rabbit Anti-UBE2E3/APC Conjugated antibody
中文名稱 APC標記的泛素蛋白連接酶E3抗體
別    名 Homologous to yeast UBC4/5; UB2E3_HUMAN; UBC E4; Ubc M2; UBC4/5 homolog; UBCE 4; UBCE4; UBCH 9; UBCH9; UbcM2; UBE2 E3; UBE2E3; Ubiquitin carrier protein; Ubiquitin carrier protein E3; Ubiquitin conjugating enzyme E2 23 kDa; Ubiquitin conjugating enzyme E2 E3; Ubiquitin conjugating enzyme E2E 3; Ubiquitin conjugating enzyme UBCH 9; Ubiquitin conjugating enzyme UBCH9; Ubiquitin protein ligase; Ubiquitin protein ligase E3; Ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UBE2E3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.

Subunit:
The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus (By similarity). Interacts with NEDD4L.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.

Tissue Specificity:
Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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