97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色吊丝最新永久免费视频,上课被cao的好爽高潮免费视频,91视频一88av
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-RNF31/BF647 Conjugated antibody (bs-9241R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9241R-BF647
英文名稱 Rabbit Anti-RNF31/BF647 Conjugated antibody
中文名稱 BF647標記的環指蛋白31抗體
別    名 HOIL 1L interacting protein; HOIL-1-interacting protein; HOIL-1L interacting protein; HOIL1L interacting protein; HOIP; RING finger protein 31; RNF31; RNF31_HUMAN; ZIBRA; Zinc in between ring finger ubiquitin associated domain; Zinc in-between-ring-finger ubiquitin associated domain; Zinc in-between-RING-finger ubiquitin-associated domain protein; FLJ10111; FLJ23501  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質和核信號  信號轉導  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 118kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF31/HOIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.

Function:
E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('M-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types.

Subunit:
Interacts with MUSK. Component of the LUBAC complex (linear ubiquitin chain assembly complex) which consists of SHARPIN, RBCK1 and RNF31. LUBAC has a MW of approximative 600 kDa suggesting a heteromultimeric assembly of its subunits. Associates with the TNF-R1 signaling complex (TNF-RSC) in a stimulation-dependent manner. Contains 1 UBA domain.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in both normal and transformed breast epithelial cell lines.

Similarity:
Contains 1 IBR-type zinc finger.
Contains 3 RanBP2-type zinc fingers.
Contains 2 RING-type zinc fingers.
Contains 1 UBA domain.

Database links:

Entrez Gene: 55072 Human

Entrez Gene: 268749 Mouse

Omim: 612487 Human

SwissProt: Q96EP0 Human

SwissProt: Q924T7 Mouse

Unigene: 375217 Human

Unigene: 434081 Human

Unigene: 23748 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 深夜视频在线免费 | 久久特级av一级毛片 | 99er视频| 性猛交╳XXX乱大交 精品国产不卡 | 永久免费A∨片在线观看 | 久久精品亚洲成在人线av麻豆 | 欧美最厉害的喷水VIDEOS | 综合成人亚洲偷自拍色 | A级日本乱理伦片免费入口 四虎精品免费 | 国产又黄又硬又粗 | 精品国产欧美日韩不卡在线观看 | 国产免费自拍视频 | 伊人久久综合一区二区 | 亚洲国产综合精品中久 | 天天躁日日躁aaaa视频 | 欧美一级日韩一级亚洲一级 | 日韩高清一级 | 国产AV无码精品国产精品 | 久久人人槡人妻人人玩夜色AV | 床震吃胸膜奶免费视频 | 日韩一区二区三区四区区区 | 曰韩av在线 | 免费网站看v片在线a | 69久久 | 美女自卫慰黄网站 | 一级国产| 老年人一级黄色片 | 久久久91精品国产一区二区精品 | 国产无遮挡无码视频免费软件 | 亚洲精品秘在线看 | 免费不卡欧美自拍视频 | 四虎永久免费 | 粉嫩av一区二区三区免费观看 | 老师粉嫩小泬喷水视频90 | 欧美乱妇日本无乱码特黄大片 | 国产精品老牛影院av | 精品国产不卡 | 91精品国产综合久久男男 | 一本久久知道综合久久 | 亚洲精品中文字幕无码av | 综合欧美亚洲日本 |