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Rabbit Anti-DCAF13/PE Conjugated antibody (bs-9395R-PE)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9395R-PE
英文名稱 Rabbit Anti-DCAF13/PE Conjugated antibody
中文名稱 PE標記的DCAF13蛋白抗體
別    名 DCA13_HUMAN; DCAF13; DDB1 and CUL4 associated factor 13; DDB1- and CUL4-associated factor 13; DKFZP564O0463; GM83; HSPC064; WD repeat and SOF domain-containing protein 1; WD repeats and SOF1 domain containing; WDSOF1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Horse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DCAF13
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Function:
Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Subunit:
Interacts with DDB1.

Subcellular Location:
Nucleus, nucleolus (By similarity).

Similarity:
Contains 7 WD repeats.

Database links:

Entrez Gene: 25879 Human

Entrez Gene: 223499 Mouse

Entrez Gene: 100173913 Orangutan

SwissProt: Q5ZLK1 Chicken

SwissProt: Q9NV06 Human

SwissProt: Q6PAC3 Mouse

SwissProt: Q5R4T8 Orangutan

Unigene: 532265 Human

Unigene: 321937 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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