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Rabbit Anti-CHES1/BF350 Conjugated antibody (bs-13899R-BF350)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13899R-BF350
英文名稱 Rabbit Anti-CHES1/BF350 Conjugated antibody
中文名稱 BF350標記的CHES1蛋白抗體
別    名 C14orf116; Checkpoint suppressor 1; CHES1; Forkhead box protein N3; Foxn3; FOXN3_HUMAN; FXN3; FXN3; PRO1635.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CHES1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

Function:
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).

Subcellular Location:
Nucleus.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 1112 Human

Entrez Gene: 71375 Mouse

Entrez Gene: 314374 Rat

Omim: 602628 Human

SwissProt: O00409 Human

SwissProt: Q499D0 Mouse

Unigene: 434286 Human

Unigene: 621371 Human

Unigene: 341972 Mouse

Unigene: 392143 Mouse

Unigene: 448530 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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