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Rabbit Anti-DDX24/RBITC Conjugated antibody (bs-14219R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14219R-RBITC
英文名稱 Rabbit Anti-DDX24/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的ATP依賴解旋酶DDX24抗體
別    名 ATP dependent RNA helicase DDX24; ATP-dependent RNA helicase ddx24; DDX 24; ddx24; DDX24_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 24; DEAD box protein 24; DEAD/H (Asp Glu Ala Asp) box polypeptide 24; S. cerevisiae CHL1 like helicase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  神經生物學  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 120kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DDX24
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008]

Function:
ATP-dependent RNA helicase.

Tissue Specificity:
Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.

Database links:

Entrez Gene: 57062 Human

Entrez Gene: 27225 Mouse

Omim: 606181 Human

SwissProt: Q9GZR7 Human

SwissProt: Q9ESV0 Mouse

Unigene: 510328 Human

Unigene: 3935 Mouse

Unigene: 475067 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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