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Rabbit Anti-ZIC5/BF594 Conjugated antibody (bs-12147R-BF594)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-12147R-BF594
英文名稱(chēng) Rabbit Anti-ZIC5/BF594 Conjugated antibody
中文名稱(chēng) BF594標(biāo)記的鋅指蛋白ZIC5抗體
別    名 zic5; ZIC5_HUMAN; Zinc finger protein of the cerebellum 5; Zinc finger protein ZIC 5.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZIC5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13.

Function:
Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the GLI C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.

Database links:

Entrez Gene: 85416 Human

Entrez Gene: 65100 Mouse

Entrez Gene: 361095 Rat

SwissProt: Q96T25 Human

SwissProt: Q7TQ40 Mouse

Unigene: 508570 Human

Unigene: 390761 Mouse

Unigene: 198356 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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