97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产成人麻豆免费观看,成年免费在线,狠狠做五月深爱婷婷
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-E2F7/BF594 Conjugated antibody (bs-13045R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13045R-BF594
英文名稱 Rabbit Anti-E2F7/BF594 Conjugated antibody
中文名稱 BF594標記的轉錄調節因子E2F7抗體
別    名 E2F 7; E2F transcription factor 7; E2F-7; E2f7; E2F7_HUMAN; FLJ12981; Transcription factor E2F7.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human E2F7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5, E2F-6 and E2F-7 each of which forms heterodimers with a second protein, DP-1, forming an “active” E2F transcriptional regulatory complex.

Function:
Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription (By similarity). Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession.

Subunit:
Homodimer and heterodimer: mainly forms homodimers and, to a lesser extent, heterodimers with E2F8. Dimerization is important for DNA-binding. Interacts with HIF1A.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the E2F/DP family.

Database links:

Entrez Gene: 144455 Human

Entrez Gene: 52679 Mouse

Entrez Gene: 314818 Rat

Omim: 612046 Human

SwissProt: E1BE02 Cow

SwissProt: Q96AV8 Human

SwissProt: Q6S7F2 Mouse

SwissProt: D4A4D7 Rat

Unigene: 416375 Human

Unigene: 11747 Mouse

Unigene: 211183 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: yy6080午夜我不卡 | japanese国产打屁股网站 | 国产无人区码一码二码三MBA | 让少妇爽到高潮视频 | 天天躁日日躁狠狠躁欧美老妇小说 | 日本一级片在线观看 | 国产午夜日韩不卡一区 | 深夜视频在线免费 | 野花社区www官网在线观看 | 日本高清视频在线观看 | 精品国产不卡 | 免费人成视频在线观看视频 | 美女国产毛片a区内射 | www.5xpxp.com毛片 日韩精品免费一区二区三区竹菊 | 成人活性生交大片免费看 | 91视频免费在观看 | 熟妇人妻无乱码中文字幕真矢织江 | 午夜嘿嘿 | 国产精品99久久久久久小说 | 一级淫片aaa | 中文国产三级 | 日韩精品人妻系列无码AV东京 | 涩涩av | 午夜国产免费 | 人妻系列无码专区无码专区 | 让少妇爽到高潮视频 | 中文字幕+乱码+中文乱码 | 亚洲精品3p| 一级在线播放 | 色八a级在线观看 | 国产精品欧美精品 | 欧美国产三级 | 大地资源在线观看免费高清官网 | 国产免费拔擦拔擦8x高清在线人 | 99视频在线精品 | 国产精品自产拍在线观看55亚洲 | 精品亚洲一区二区三区在线观看 | 特黄色一级片 | aaaa一级片 | 久久精品人 | 九九在线中文字幕无码 |