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Rabbit Anti-Argonaute 4/Gold Conjugated antibody (bs-12518R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-12518R-Gold
英文名稱 Rabbit Anti-Argonaute 4/Gold Conjugated antibody
中文名稱 膠體金標記的真核翻譯起始因子2C4抗體
別    名 eIF2C4; 5730550L01Rik; Ago 4; Ago4; AGO4_HUMAN; Argonaute4; EIF 2C 4; eIF-2C 4; eIF2C 4; Eif2c4; eukaryotic translation initiation factor 2C 4; eukaryotic translation initiation factor 2C; hAgo4; KIAA1567; Piwi/Argonaute family protein meIF2C4; Protein argonaute-4.   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 97kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Argonaute 4/eIF2C4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a cluster of closely related family members including argonaute 3, and eukaryotic translation initiation factor 2C, 1. [provided by RefSeq, Jul 2008]

Function:
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).

Subunit:
Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.Cellular localization.

Database links:

Entrez Gene: 192670 Human

Entrez Gene: 76850 Mouse

Entrez Gene: 298533 Rat

Omim: 607356 Human

SwissProt: Q9HCK5 Human

SwissProt: Q8CJF8 Mouse

Unigene: 471492 Human

Unigene: 86705 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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