97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
蜜桃传免费看片www,国产成人手机在线视频,91新视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CMKLR1/Cy5 Conjugated antibody (bs-10185R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10185R-Cy5
英文名稱 Rabbit Anti-CMKLR1/Cy5 Conjugated antibody
中文名稱 Cy5標記的趨化樣因子受體1抗體
別    名 Chemokine receptor-like 1; CHEMR23; ChemR23; DEZ; Chemokine like receptor 1; G protein coupled receptor ChemR23; G protein coupled receptor DEZ; CML1_HUMAN ; Orphan G protein coupled receptor.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  染色質和核信號  G蛋白偶聯受體  表觀遺傳學  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 42kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from rat CMKLR1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Chemokine-Like Receptor 1 (CMKLR1) is a serpentine transmembrane G-protein linked receptor. It is an orphan chemoattractant receptor, also known as ChemR23 or DEZ. CMKLR1 is expressed on the surface of monocyte-derived immature dendritic cells and peripheral plamacytoid dendritic (pDC) cells; but not on myeloid dendritic (mDC) cells, monocytes and lymphocytes. The expression of CMKLR1 on pDC is down-regulated after activation. Chemerin (TIG2) is a natural ligand of CMKLR1. The interaction of CMKLR1 with Chemerin induces pDC activation and chemotaxis. It has been shown that CMKLR1 is a coreceptor for several strains of SIV and HIV-1. CMKLR1 is a potential useful marker for distinguishing pDCs and mDCs.

Function:
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Subcellular Location:
Cell membrane.

Tissue Specificity:
Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T cells. Expressed on endothelial cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 1240 Human

Entrez Gene: 14747 Mouse

Entrez Gene: 60669 Rat

Omim: 602351 Human

SwissProt: Q99788 Human

SwissProt: P97468 Mouse

SwissProt: O35786 Rat

Unigene: 197143 Human

Unigene: 5196 Mouse

Unigene: 44465 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 m.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久99精品久久久久久水蜜桃 | 女人被男人桶爽视频网站 | oidgrαnny日本老熟妇 | 中文人妻无码一区二区三区 | 国产丝袜一区视频在线观看 | 久久不见久久见www免费视频 | 国产农村妇女一区二区三区 | 国产精品国三级国产av | 91精品国产乱码久久久软件 | 国产成人亚洲精品无码H在线 | 麻豆视频免费在线观看 | 国产91精品一区二区三区四区 | 少妇在宾馆高潮不断狂叫床 | 欧美亚洲系列 | 国产精品自在线拍亚洲另类 | 说英雄谁是英雄免费观看 | 亚洲精品无码久久久久AV老牛 | 亚洲精品一区二区三区中文字幕 | 92国产精品偷窥熟女精品视频 | 国产免费一级片 | 91九色性视频 | 国产午夜精品久久久久久免费视 | 久久久久久久人妻无码中文字幕爆 | 丁香五月色情婷婷在线观看 | 欧美精品福利视频 | 2017最新高清无码网站 | 亚洲在线免费视频 | 999视频精品 | 成人午夜激情视频 | 色综合激情一区二区三区 | 亚洲精品久久久久久久久久 | 牲高潮99爽久久久久777 | 精品国产免费一区二区三区四区 | 国产精品美女久久久久久 | 人妻丰满熟妇无码区免费 | 亚洲色偷偷av男人的天堂 | 日本永久免费a∨在线视频 91精品国产综合久久小仙女图片 | 免费国产黄线在线播放 | 超碰91资源 | 亚洲欧美日韩天堂一区二区 | 日韩在线一二三 |