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Rabbit Anti-ELK3/BF350 Conjugated antibody (bs-14565R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-14565R-BF350
英文名稱 Rabbit Anti-ELK3/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的血清反應(yīng)因子輔助蛋白SAP2抗體
別    名 ELK3; ELK3, ETS domain protein (SRF accessory protein 2); ELK3_HUMAN; ERP; ETS domain protein; ETS domain-containing protein Elk-3; ETS related protein ERP; ETS related protein NET; ETS-related protein ERP; ETS-related protein NET; NET; SAP 2; SAP-2; SAP2; Serum response factor accessory protein 2; SRF accessory protein 2.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELK3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by RefSeq, Jul 2008]

Function:
May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.

Subunit:
Interacts with CTBP1.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Database links:

Entrez Gene: 2004 Human

Entrez Gene: 417919 Chicken

Entrez Gene: 541125 Cow

Entrez Gene: 482613 Dog

Entrez Gene: 13713 Mouse

Entrez Gene: 362871 Rat

Omim: 600247 Human

SwissProt: P41970 Human

SwissProt: P41971 Mouse

Unigene: 46523 Human

Unigene: 4454 Mouse

Unigene: 196088 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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