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Rabbit Anti-EMR4/PE Conjugated antibody (bs-14589R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-14589R-PE
英文名稱 Rabbit Anti-EMR4/PE Conjugated antibody
中文名稱 PE標記的EMR4蛋白抗體
別    名 EGF like module containing mucin like hormone receptor like 4; EGF TM7 receptor EMR4; EMR4P; EMR4_HUMAN; FIRE; G protein coupled receptor 127; G protein coupled receptor PGR16; GPR127; PGR16; Putative EGF like module containing mucin like hormone receptor like 4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉導  細胞粘附分子  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EMR4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]

Function:
EMR4 could mediate the cellular interaction between myeloid cells and B-cells.

Subunit:
Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit) (By similarity).

Subcellular Location:
Cell Membrane; multi pass membrane protein

Post-translational modifications:
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 2 EGF-like domains.
Contains 1 GPS domain.

Database links:

Entrez Gene: 326342 Human

Omim: 612305 Human

SwissProt: Q86SQ3 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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