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Rabbit Anti-IMPACT/Gold Conjugated antibody (bs-16625R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-16625R-Gold
英文名稱 Rabbit Anti-IMPACT/Gold Conjugated antibody
中文名稱 膠體金標記的IMPACT蛋白抗體
別    名 IMPACT; Impact homolog (mouse); Impact homolog; impact RWD domain protein; IMPCT_HUMAN; Imprinted and ancient gene protein homolog; MGC33718; Protein IMPACT; RWD domain containing 5; RWDD5.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Cow, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IMPACT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.

Function:
Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

Subunit:
Interacts with GCN1/GCN1L1 (By similarity).

Subcellular Location:
Cytoplasm (By similarity). Note=May be associated with polysomes (By similarity).

Tissue Specificity:
Widely expressed. Expressed at high level in brain.

Similarity:
Belongs to the IMPACT family.
Contains 1 RWD domain.

Database links:

Entrez Gene: 55364 Human

Entrez Gene: 100009333 Rabbit

SwissProt: Q9P2X3 Human

SwissProt: Q5GFD8 Rabbit

Unigene: 515317 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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