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Rabbit Anti-INO80B/PE-Cy5.5 Conjugated antibody (bs-16661R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-16661R-PE-Cy5.5
英文名稱 Rabbit Anti-INO80B/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的PAP1結合蛋白抗體
別    名 2510009I23Rik; hIes2; high mobility group AT hook 1 like 4; High mobility group AT-hook 1-like 4; HMG1YL4; Hmga1l4; IES2; IES2 homolog; IN80B_HUMAN; INO80 complex subunit B; INO80B; PAP (Pim 1 associated protein) associated protein 1; PAP (Pim1 associated protein) associated protein 1; PAP 1 associated protein 1; PAP 1 binding protein; PAP 1BP; PAP-1-associated protein 1; PAP1 associated protein 1; PAP1 binding protein; PAP1BP; PAPA 1; PAPA-1; Papa1; zinc finger HIT domain containing protein 4; Zinc finger HIT domain-containing protein 4; zinc finger HIT type 4; Znhit4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human INO80B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011]

Function:
Induces growth and cell cycle arrests at the G1 phase of the cell cycle. Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Subunit:
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with RP9. {ECO:0000269|PubMed:15556297, ECO:0000269|PubMed:16230350, ECO:0000269|PubMed:18922472, ECO:0000269|PubMed:21303910}.

Subcellular Location:
Nucleus. Nucleus; nucleolus.

Similarity:
Contains 1 HIT-type zinc finger.

Database links:

Entrez Gene: 83444 Human

Entrez Gene: 70020 Mouse

SwissProt: Q9C086 Human

SwissProt: Q99PT3 Mouse

Unigene: 410786 Human

Unigene: 27814 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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