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Rabbit Anti-Nfe2l3/Biotin Conjugated antibody (bs-19499R-Bio)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-19499R-Bio
英文名稱 Rabbit Anti-Nfe2l3/Biotin Conjugated antibody
中文名稱 生物素標記的NFE2相關因子樣蛋白3抗體
別    名 erythroid derived 2; like 3; NF-E2-related factor 3; NF2L3_HUMAN; NFE2-related factor 3; Nfe2l3; NRF3; Nuclear factor; Nuclear factor erythroid 2-related factor 3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Cow, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nfe2l3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

Function:
Activates erythroid-specific, globin gene expression.

Subunit:
Heterodimer with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE).

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the bZIP family. CNC subfamily.
Contains 1 bZIP domain.

Database links:

Entrez Gene: 9603 Human

Omim: 604135 Human

SwissProt: Q9Y4A8 Human

Unigene: 404741 Human

Unigene: 712898 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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